Novel Therapies

 

Chemokines

Chemokine Therapeutics Video

Chemokine Therapeutics on BusinessTV

The chemokine network in cancer - much more than directing cell movement

THE CXCR4 ANTAGONIST CTCE-9908 INHIBITS SDF-1-INDUCED ANGIOGENESIS

Messenger RNAExpression Levels of CXCR4 Correlatewith Metastatic Behavior and Outcome in Patients with Osteosarcoma

CXCR4 and VEGF expression in the primary site and the metastatic site of human osteosarcoma: analysis within a group of patients, all of whom developed lung metastasis

Chemokine receptor CXCR4-1 integrin axis mediates tumorigenesis of osteosarcoma HOS cells

 

Ellagic Acid

Pharmacokinetic study of ellagic acid in rat after oral administration of pomegranate leaf extract

Combined inhibition of PDGF and VEGF receptors by ellagic acid, a dietary-derived phenolic compound

Low Concentrations of Quercetin and Ellagic Acid Synergistically Influence Proliferation, Cytotoxicity and Apoptosis in MOLT-4 Human Leukemia Cells1–3

 

mTor Inhibitor

Ariad mTor video

ARIAD REPORTS TUMOR REGRESSION WITH AP23573 AS A SINGLE AGENT IN PATIENTS WITH RELAPSED AND/OR REFRACTORY CANCER

An expanding role for mTOR in cancer

Rapamycin Inhibits Ezrin-Mediated Metastatic Behavior in a Murine Model of Osteosarcoma

 

Rexin-G

About Rexin-G

 

 

Valproic Acid

Valproic Acid Inhibits Angiogenesis in Vitro and in Vivo

The Histone Deacetylase (HDAC) Inhibitor Valproic Acid as Monotherapy or in Combination with All- Trans Retinoic Acid in Patients with Acute Myeloid Leukemia

Valproic Acid defines a novel class of HDAC inhibitors inducing differention f transformed cells

Epigenetic therapy of cancer: past, present and future

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

 

Zoledronic Acid

Zoledronic Acid Suppresses Lung Metastases and Prolongs Overall Survival of Osteosarcoma-Bearing Mice

Anticancer Effects of Zoledronic Acid against Human Osteosarcoma Cells