Methotrexate

 

Historical Articles

Favorable Response of Metastatic Osteogenic Sarcoma To Pulse High-Dose Methotrexate With Citrovoum Rescue and Radiation Therapy

Adjuvant Methotrexate and Citrovorum-Factor Treatment Of Osteogenic Sarcoma

New approaches to cancer chemotherapy with Methotrexate

Methotrexate: Distribution in Cerebrspinal Fluid After Intravenous, Ventricular and Lumbar Injections

New approaches to cancer chemotherapy with Methotrexate

Correspondence Treatment Methotrexate for Osteosarcoma

 

Managing Toxicity

Optimal Management of Methotrexate Intoxication in a Child with Osteosarcoma

High-Dose Methotrexate-Induced Nephrotoxicity in Patients with Osteosarcoma Incidence, Treatment, and Outcome

Survival After Unexpected High Serum Methotrexate Concentrations in a Patient with Osteogenic Sarcoma

 

 

Pathology

Low-dose methotrexate inhibits lung metastasis and lengthens survival in rat osteosarcoma

An 19F Magnetic Resonance–Based In vivo Assay of Solid Tumor Methotrexate Resistance: Proof of Principle

a-Tocopheryl succinate alters cell cycle distribution sensitising human osteosarcoma cells to methotrexate-induced apoptosis

Low-Voltage Electrochemotherapy with Low-Dose Methotrexate Enhances Survival in Mice with Osteosarcoma

Metabolic Modification by Insulin Enhances Methotrexate Cytotoxicity in MCF-7 Human Breast Cancer Cells

 

Resistance

The Human Multidrug Resistance Protein MRP5 Transports Folates and Can Mediate Cellular Resistance against Antifolates

Mechanisms of Methotrexate Resistance in Osteosarcoma

 

Outcome

          Methotrexate levels and outcome in osteosarcoma.

High-Dose Methotrexate Chemotherapy

Influence of Methotrexate Dose Intensity on Outcome of Patients with High Grade Osteogenic Osteosarcoma

High-Dose Methotrexate Pharmacokinetics and Outcome of Children and Young Adults with Osteosarcoma