Intraarterial Chemotherapy

1975 Osteosarcoma intra-arterial Kyoto, Japan

1981  The therapy of osteosarcoma by intra-arterial cis-platinum an limb preservation.

1981  Intra-arterial cis-platinum for patients with inoperable skeletal tumors.

1981 Systemic Hypertension: A complication of intra-arterial cisplatin infusion

1983 Osteosarcoma: intra-arterial treatment of the primary tumor with cis-diammine-dichloroplatinum II (CDP). Angiographic, pathologic, and pharmacologic studies.

1985    Comparison of intra-arterial cis-diamminedichloroplatinum II with high-dose methotrexate and citrovorum factor rescue in the treatment of primary osteosarcoma

1987  Regional chemotherapy with the use of cisplatin and doxorubicin as primary treatment for advanced sarcomas in shoulder, pelvis, and thigh

1989 Systemic doxorubicin and intraarterial cisplatin preoperative chemotherapy plus postoperative adjuvant chemotherapy in patients with osteosarcoma

1989 Effect of cumulative courses of intraarterial cis-diamminedichloroplatin-II on the primary tumor in osteosarcoma.

1990 Pediatric osteosarcoma. Successful retreatment of relapsed primary tumor and soft tissue recurrence with intraarterial cis-diamminedichloroplatin-II

1991 Intraarterial cisplatin in the management of stage IIB osteosarcoma in the pediatric and adolescent age group

1992 Effect of chemotherapy combined with caffeine for osteosarcoma Japan

1993 Treatment of osteosarcoma: experience of the Cooperative Osteosarcoma Study Group (COSS)

1993 Pediatric osteosarcoma: treatment of the primary tumor with intraarterial cis-diamminedichloroplatinum-II (CDP)--advantages, disadvantages, and controversial issues

1993 Intraarterial chemotherapy for osteosarcoma: does the result really justify the effort?

1998 Japan  Caffeine-assisted chemotherapy and minimized tumor excision for nonmetastatic osteosarcoma.  

1999 Japan Marginal excision for osteosarcoma with caffeine assisted chemotherapy pdf

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1999 Combined pre-operative chemotherapy with intra-arterial cisplatin and continuous intravenous adriamycin for high grade osteosarcoma

2003 Superior survival in treatment of primary nonmetastatic pediatric osteosarcoma of the extremity.