Biology of Osteosarcoma

 

Overview

Biology of Osteogenic Sarcoma

Biology of Childhood Osteogenic Sarcoma and Potential Targets for Therapeutic Development: Meeting Summary

Biology and Therapeutic Advances for Pediatric Osteosarcoma

Cytogenetics and Molecular Biology of Osteosarcoma

Osteosarcoma: Basic Science and Clinical Implications

 

Microarrays

Gene Amplifications in Osteosarcoma—CGH Microarray Analysis

Transforming growth factor-beta 1 modulates the expression of vascular endothelial growth factor by osteoblasts

High-Resolution Mapping of Amplifications and Deletions in Pediatric Osteosarcoma by Use of CGH Analysis of cDNA Microarrays

 

Other Articles

Messenger RNAExpression Levels of CXCR4 Correlatewith Metastatic Behavior and Outcome in Patients with Osteosarcoma

Two novel tumor suppressor gene loci on chromosome 6q and 15q in human osteosarcoma identified through comparative study of allelic imbalances in mouse and man

Genome-wide array comparative genomic hybridization analysis reveals distinct amplifications in osteosarcoma

Loss of imprinting of IGF2 and H19 in osteosarcoma is accompanied by reciprocal methylation changes of a CTCF-binding site

An Expression Signature Classifies Chemotherapy-Resistant Pediatric Osteosarcoma

Terminal osteoblast differentiation, mediated by runx2 and p27 KIP1, is disrupted in osteosarcoma

 

Abstracts

Scientists at Broad Institute (Cambridge, MA) search Canine Osteosarcoma DNA for clues to cancer

Detection of hypothetical proteins in 10 individual human tumor cell lines

Frequent amplification and rearrangement of chromosomal bands 6p12-p21 and 17p11.2 in osteosarcoma

Oncogene alterations in primary, recurrent, and metastatic human bone tumors

Spectral karyotyping identifies recurrent complex rearrangements of chromosomes 8, 17, and 20 in osteosarcomas.

Telomere stability genes are not mutated in osteosarcoma cell lines